Although children with lupus fare better now than they did 10-20 years ago, racial and ethnic minorities with childhood lupus continue to have worse health outcomes compared to their white peers. The neighborhoods in which these children live can have a deep impact on their opportunity to achieve optimal health and well-being. Racial residential segregation can perpetuate poor neighborhood conditions, which may contribute to even greater racial disparities in childhood lupus outcomes in certain places. This project will utilize a place-based approach to study whether different dimensions of residential segregation and neighborhood-based opportunity can be used to identify children at the highest risk for poor lupus outcomes. These measures could be employed at the provider, hospital or policy level to determine where and to whom additional services or community interventions should be directed in order to reduce health inequities.