Fingerprinting Childhood Lupus

Project Period:

Grant Category:
EC Biosample Stimulus Fund

Disease Area:

Our hypothesis is that childhood SLE includes distinct biological subgroups that can be identified through multi-modal clinical, immune, and genetic profiling. Our approach is to perform deep immunophenotyping on a small number of patients (non-CARRA) and to extend findings (genetic and, where possible, whole-blood RNAseq) to the CARRA cohort to establish generalizability.


Peter Nigrovic

Boston Children's Hospital

Related Awarded Grants

Disease Area:
Juvenile Idiopathic Arthritis (JIA), Juvenile Dermatomyositis (JDM), Scleroderma, Juvenile Myositis, LUPUS, Rheumatoid Arthritis

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Disease Area:
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