Childhood Lupus (SLE)
Why pediatric SLE research matters
Pediatric lupus is more aggressive than adult-onset disease, with higher risks of kidney failure, neuropsychiatric complications, and long-term organ damage. CARRA’s SLE Research Committee leads a unified effort to improve outcomes for these vulnerable children.
What your gift supports
Your investment powers research across five workgroups:
Antiphospholipid Syndrome
CLUTCH
Neuropsychiatric Lupus
SLE Nephritis
JDM/SLE Dermatology
A breakthrough moment for pediatric lupus
Recent CAR-T successes in systemic lupus erythematosus have opened a door once thought permanently closed: the possibility of durable remission without lifelong immunosuppression.
Combined with:
CARRA Registry’s modernized real-world evidence platform
CARRA–FDA regulatory alignment
CARRA’s national research network
…this is a once-in-a-generation opportunity to transform care for children with lupus.
Patient & family engagement: central to SLE progress
Your support ensures families help shape the science. Gifts to SLE research help:
- Integrate patient voices
- Support PFAC involvement
- Expand access for diverse families
- Ensure research reflects real-world needs
Cross-cutting infrastructure: powering SLE discovery
Your gift strengthens:
- Registry-based studies and biosample collection
- Scientific staff and data teams
- Clinical informatics and equity initiatives
- Genomic data management
- CTP development and updates
Make your gift
Your support helps children with lupus avoid organ damage, achieve remission, and live fuller lives.
Talk with our team
Have questions or want to talk it through? I’d love to hear from you.
Caitlin Williams
Director of Individual and Foundation Giving
CARRA is a 501(c)(3) nonprofit. 85% of expenses are for programs and services.