Defining and Characterizing Diagnostic Delay in Juvenile Idiopathic Arthritis

Project Period:
2024-2027

Grant Category:
MCDA

Disease Area:
Juvenile Idiopathic Arthritis (JIA)

Without early and aggressive treatment of juvenile idiopathic arthritis (JIA), patients can suffer destructive joint damage, long-lasting pain, and disability. There are safe and effective options for managing arthritis that not only treat but also halt disease progression. Unfortunately, an accurate diagnosis often takes many months, causing families unnecessary pain and stress. First, this project will use a national claims database to characterize healthcare utilization in the year preceding JIA diagnosis and use machine learning to generate archetypal trajectories to diagnosis. Second, this project will leverage a panel of CARRA physicians and parent stakeholders to establish a consensus definition of diagnostic delay. This research will lay the foundation for future work to design interventions to eliminate barriers to timely, accurate, and equitable diagnosis for patients with JIA.

Investigators

Anna Costello, MD

The Children's Hospital of Philadelphia

Related Awarded Grants

Disease Area:
Juvenile Idiopathic Arthritis (JIA)

Genetic Ancestry Powered studies (GAPs) in JIA

Disease Area:
Juvenile Idiopathic Arthritis (JIA)

Pilot of Adalimumab Withdrawal