In a subset of children with sJIA, a new form of lung disease is being detected as a serious complication. It seems most likely that this is a new and increasing problem, rather than better detection of a long-standing rare complication. Our recent work identified strong candidate risk factors for this new disease, which, if confirmed, will impact clinical management of children with sJIA. We have extended our study to analyze over 45 new cases of sJIA complicated by lung disease to confirm risk factors and possibly identify additional aspects of this disease. Data from the CARRA registry will be useful for comparing children with lung disease to a larger group of children with sJIA.