Pediatric rheumatologists have several options to treat juvenile idiopathic arthritis (JIA). The STOP-JIA study looked at three treatment strategies for polyarticular JIA to see which worked best over time. These included starting with standard medications like methotrexate, and adding newer ones (like biologics) later (Step Up), starting both together (Early Combination), or starting with the newer medication first (Biologic First). While all approaches worked similarly at first, EC led to faster and longer-lasting improvement. Since there is now 6 years of follow-up data for many STOP-JIA participants, we’d like to see how often those patients changed their medication plans over the 5 years, and how the start time of biologic therapy affected their longer-term outcomes.