Registry Co-Principal Investigator
Letter of Intent (LOI) due June 14, 2021
The CARRA Registry Co-Principal Investigator (Co-PI) is a key member of the leadership team responsible for overseeing research policies and procedures regarding the CARRA Registry and Registry sites to fulfill its goal of understanding long-term outcomes and the long- and short-term safety and effectiveness of the medications used to treat pediatric rheumatic diseases. The co-PI position reports to the current CARRA Registry PIs.
The Co-PI will work closely with current CARRA Registry Principal Investigators, the Scientific Director, the Operations Lead at the DCRI (the Registry's Coordinating Center) and CARRA Registry Operations team, to address current and potential issues with the conduct of the Registry and support ongoing partnership development with pharmaceutical partners. The Co-PI must have great attention to detail, be solutions-driven, and be motivated by a collaborative research environment.
The Co-PI will hold a non-voting seat on the CARRA Research and Registry Oversight Committee, the Board-appointed body that oversees the Registry and will participate in related activities and initiatives as required. The position would account for 10% of an individual’s time (1.2 calendar months, $200,000 maximum salary) over a 1-year term with potential for 3-year appointment (renewable) as external CARRA Registry PI at 20% effort (2.4 calendar months).
Position responsibilities include, but are not limited to the following:
- Support the efforts of CARRA Registry PI’s to address current and potential issues with the conduct of the Registry:
- Oversee CARRA’s research policies and procedures regarding the CARRA Registry and Registry sites.
- Review and make recommendations regarding new study proposals that wish to utilize the CARRA Registry or CARRA Registry sites, and/or seek endorsement from the RROC as a CARRA research project or activity.
- Facilitate the implementation of new projects that utilize the CARRA Registry and/or CARRA research sites and monitor their performance.
- Ensure timely generation of publications for CARRA’s Registry and sub-studies.
- Ensure timely analysis of research results and review of performance metrics for CARRA’s Registry and sub-studies.
- Propose annual and long-term goals and objectives for CARRA’s Registry and sub-studies for review and approval by the Board. These include goals for Registry enrollment, data quality, long term follow-up and rates of retention.
- Oversee and evaluate performance of the CARRA Registry’s contracted coordinating center.
- Co-PI responsibilities include:
- Oversee Registry protocol and performance at sites, including assisting with site performance issues as needed
- Plan and participate in grant development furthering CARRA Registry infrastructure and use.
- Review protocol and CRF changes
- Liaise with Registry Parent/Patient Advisory Committee (RPAC)
- Serve as a mentor to Registry Associates
- Be involved in selecting and co-authoring manuscripts as well as related manuscript RFAs
- Provide critical input and planning for the annual Registry retreat, annual meeting at DCRI, Registry-related activities at CARRA Annual Meeting, etc.
- Provide critical input and review on Registry operations budget
- Participate in regular conference calls/meetings which include but are not limited to:
- Weekly RROC calls
- Monthly meetings with the Registry Operations team
- Monthly Registry site calls
- Monthly Registry Retreat planning calls
- Monthly Registry and Informatics Associate Program calls
- Monthly Biobank Operations call
- Calls with pharma project teams and leadership as needed for existing studies
- Calls with pharma as needed to discuss potential new projects
- Calls for ongoing Registry-related projects and studies (e.g., STOP-JIA, Recapture, etc.)
- Quarterly Board of Directors calls (as needed)
- Annual CARRA-DCRI Registry Retreat at DCRI (if virtual)
- Travel as representative of CARRA, including but not limited to attending the following meetings as needed:
- Annual ACR conference for participation in business development meetings with pharmaceutical companies
- CARRA Annual Scientific Meeting
- Annual CARRA Registry Investigator and Study Coordinator Retreat
- Annual CARRA-DCRI Registry Retreat at DCRI
- PReS annual conference
- Meetings with pharmaceutical companies as needed
- Applicants must be current CARRA members, have completed a pediatric rheumatology fellowship and be employed as a pediatric rheumatologist in the United States or Canada. An advanced degree and/or training in clinical research or epidemiology is desirable but not required.
- Previous experience with the CARRA Registry is required, including serving as a Registry site PI, holding a CARRA Registry position, authoring Registry publications, supporting development of Registry CRFs, experience applying for and using Registry data, or other experience.
- Previous experience as a PI of a grant (e.g., CARRA grant, Foundation, NIH, PCORI, etc.) is required.
- Publication track record is also required.
- Applicants for CARRA’s Assistant Scientific Director are also eligible to apply for the Co-PI position, with the understanding that both positions will not be awarded to a single individual.
- A Letter of Intent (LOI) which should include a CV is due by June 14, 2021. Registry leadership will provide a response within one week.
- Full applications are due by July 16, 2021.
- CARRA Registry leadership will review all applications and interview the top candidates. The position will be appointed by the CARRA Board of Directors, at the recommendation of Registry leadership. All applicants will be notified of the outcome of the selection process by November 1, 2021.
The position would account for 10% of an individual’s time (1.2 calendar months, $200,000 maximum salary) over a 1-year term starting January 1, 2022 with potential for 3-year appointment (renewable) as external CARRA Registry PI at 20% effort (2.4 calendar months).
A Letter of Intent (LOI) must be submitted and approved prior to application. The LOI should be a one-page signed letter, accompanied by a CV, which includes:
- Name and institution of investigator
- Summary of qualifications
Applications must consist of the following materials as individual PDF documents:
- NIH Biosketch (maximum limit of 5 pages)
- Personal Statement: One-page (single-spaced, 12-point Calibri font, 1-inch margins) statement describing what you hope to contribute and to gain from this experience, as well as how it would fit into your long-term career goals.
- Annotated personal bibliography of 3 publications most significant to your research career.
- Institutional Letter of Support: Letter signed by division chief or chair stating that there will be 10% protected effort for these activities, with potential for up to 20% effort following one calendar year.
- Letter of Recommendation: Signed letter of recommendation from a CARRA member other than the division chief supporting your candidacy.
- References: Provide the names and contact information for two references to call. At least one reference must be a CARRA member outside of your institution who has worked with you on CARRA activities.
An application link will be shared with eligible candidates in the LOI response.
Email [email protected] if you have questions about the application process or about the position.