CARRA-Arthritis Foundation Transdisciplinary Research Grant
This funding opportunity is intended to support the development and implementation of a clinical or translational project capable of advancing knowledge applicable to multiple pediatric rheumatic diseases. Examples of transdisciplinary areas of study appropriate for this grant mechanism include, but are not limited to, mental health, reproductive health, implementation science, cardiovascular health, transition, and telemedicine/informatics. Applications comprising multidisciplinary, multi-specialty, and/or multi-organization collaborations are particularly encouraged. Applications may be for a complete clinical or translational research project or a pilot research project that, if successful, would lead to extramural funding. Preference will be given to submissions which leverage current CARRA network resources or will further develop the CARRA network.
Not currently accepting applications.
CARRA-Arthritis Foundation Transdisciplinary Research Grant Applications to Include:
- Letter of Intent (LOI)
- Project Summary/Abstract (300 work max)
- Lay Summary (150 word max)
- Resubmission Modifications, if applicable (1 page limit) (Download template: WORD)
- Resubmission modification is required if the applicant has previous submitted a similar project. Applicants should provide an explanation of what has changed from a prior application. Examples would include addressing budget differences or weaknesses the reviewers found in an earlier application.
- Specific Aims (1 page limit) (Download template: WORD)
- Research Plan (5 page limit) (Download template: WORD)
- References (no page limit) (Download template: WORD)
- Budget Table (1 page limit) (Download template: WORD)
- All Primary Investigators (PI) are required to dedicate effort on their projects which must be noted on the budget table. Requesting salary support is optional. A letter of support from your division chief documenting that the % effort is available, and confirming investigator salary (if applicable) must be submitted with each application. If the PI is the division chief, a letter from the Department Chairperson is required.
- Budget Justification (Download template: WORD)
- Total costs of salary support for PI(s) and Co-I(s) must not exceed 50% of total project costs.
- CARRA will allow up to 8% F&A (indirect) costs which must be incorporated into the project budget below. If indirect costs are requested, total costs for this project must not exceed $150,000.
- Poster printing and publication costs are not allowed.
- Travel expense requests are not permitted unless required for the conduct of research. Travel expenses to attend meetings to present this work, for example, are not allowed.
- Other expenses should be discussed with CARRA personnel prior to application submission.
- NIH-formatted Biosketches for all Principal Investigator(s), Co-Principal Investigator(s), and all Co-Investigator(s) (limit 5 pages per biosketch; please combine all biosketches into one PDF with the PI(s) biosketch listed first.)
- Letters of support
- Required for budgets that include investigator effort (include letter from division chief documenting that % effort is available, and confirming investigator salary). Total costs salary support must not exceed 50% of total project costs.
- Letters of support from collaborators, mentors and institution are highly recommended.
- Research Assurances
- Submit documentation of an Institutional Review Board (IRB) review. Funds will not be released until either 1) IRB approval letter or 2) IRB waiver/documentation that IRB has determined your project is exempt from IRB review is received.
- Awards will be relinquished if IRB approval or an IRB waiver is not received by 6 months after the project period start date.
- Appendix (limit 1 attachment)
Applicants must use the templates provided when submitting their final applications. CARRA Staff is available to assist with the application process and to answer questions. Contact us by emailing [email protected].
APPLICATIONS NOT FOLLOWING THESE INSTRUCTIONS WILL NOT BE CONSIDERED
Important Information for Transdisciplinary Research Grant Submissions
Project Period and Dates: Applicants will be notified of funding decisions in mid/late November, 2019. The project period is two years, with an expected start date of December 1.
- The funding maximum limit is $150,000 total costs over 2 years. If indirects are requested, they must be inclusive of the maximum funding amount of $150,000 and must not exceed the maximum allowable indirect amount of 8%. Please review CARRA’s statement of direct and indirect support.
- Salary support for investigators is allowable but must not exceed 50% of total project costs. Salary support will be limited to a base-salary cap of $200,000 but can include payment of local fringe rates (on top of $200,000 salary cap). Letters of support from division chiefs are required for budgets that request support for investigator effort. The letters should clearly document that the % effort requested will be allotted to the investigator and should confirm investigator salary.
- Publication, presentation, and travel costs should not be requested unless the travel is an essential part of performing the research. Other expenses should be discussed with CARRA personnel prior to application submission.
- Funds will be provided to the awardee’s institution in two payments to be set up in a sundry account and used by the principal investigator according to the project budget.
- Year 1 funding as outlined in the budget justification will be provided upfront.
- Year 2 funding will distributed following submission of a progress report at the end of year 1.
- For projects requesting budget support to cover Registry costs, requested funds will be held at CARRA and paid directly to DCRI.
- If the project is not completed within the project period, the award recipient may request a no-cost extension (NCE) for up to 12 months. Requests for NCEs can be made up to 90 days prior, but no less than 30 days prior, to the project end date. An interim progress report must be submitted with the NCE Request Form, both of which are available on the CARRA website.
- If the PI is unable to complete the project, any unexpended balance will be returned to CARRA.
- The project PI for all grants must be a current CARRA member who is up to date on membership dues and membership information (location, contact information, and membership status) is up-to-date.
- An investigator may only receive one CARRA-Arthritis Foundation grant per year (365 day period).
- Awardees from previous grant cycles who wish to submit grant applications for the upcoming deadline must have all active CARRA-Arthritis Foundation grant projects completed and have submitted a final progress report (template available on the CARRA website).
- MD applicants must be at a faculty level to be eligible to submit proposals.
- Voting Members, Emeritus Members, Research Professional Member - Investigators, Research Professional Member - Research Coordinator Members, Associate Physician Members, and Trainee Members are eligible to submit proposals.
- Priority will be given to new and/or early investigators.
- All grants must be submitted by or have a pediatric rheumatologist named as a Co-Investigator.
- Research Coordinator Member- Others, Health Care Professional Members, Fellow Members, and CARRA Executive Committee and Board of Directors members are not eligible.
- Submit a one-page Letter of Intent (see below for more details) on institutional letterhead by September 1 via the online grant submission system.
- Read the CARRA-Arthritis Foundation Transdisciplinary Grant instructions. Be sure to be compliant with formatting instructions and page limits.
- Use the document templates provided and submit your completed CARRA-Arthritis Foundation Transdisciplinary Grant application by October 1 via the online grant submission system.
- Grant applicants that intend to utilize the CARRA Registry or CARRA-related data and/or samples (including Legacy Registry and APPLE data/samples) must receive approval from the CARRA Data Sample Share Committee (DSSC) prior to submitting their grant applications.
- Applications proposing the collection of any new data or biosamples via the CARRA Registry and/or via CARRA sites, must include a letter of support (LOS) from CARRA's Research and Registry Oversight Committee (RROC).
Letter of Intent (LOI)
LOI’s are required for those submitting Collaborative Grants and are due 1 month prior (September 1) to the application deadline (October 1). The LOI should be a one-page signed letter which includes:
- A summary of the full proposal with a short description of aims of the project involved, with a clear indication of how the aims align with the intent of this application request
- Name of the PI(s) and submitting institution
- A list of key personnel and role(s)
- A description of how the project aligns with CARRA's mission.
The LOI MUST be on institutional letterhead and signed by the Principal Investigator(s).
While the LOI is an administrative requirement, it is for informational purposes only. Approval from CARRA is not needed to proceed with the full application. Investigators will receive confirmation that their LOI has been received by the CARRA grants office.
- Awardees must submit a year 1 progress report 30 days prior to the end of the first year of the project period in order to request the release of year 2 funds.
- Awardees must submit a final progress report no later than 45 days after the project period end date.
- Awardees from previous grant cycles who wish to submit grant applications for the October 2019 deadline must have all active projects completed and have submitted a final progress report (template available on the CARRA website).
- Timely provision of progress reports is taken into consideration for future eligibility for CARRA-Arthritis Foundation grants.
Presentations and Publications
- Awardees are expected to submit abstracts to CARRA and present their findings at the CARRA Annual Scientific Meeting(s) until the project is complete/final.
- Awardees are expected to submit a peer-reviewed abstract to another scientific meeting based on the funded project.
- All awardees of CARRA-Arthritis Foundation funding must abide by the procedures outlined in the CARRA Publications Policy when presenting/publishing findings from their projects. This includes submitting all abstracts and manuscripts to the CARRA Publications Committee for approval prior to submission and acknowledging the support of CARRA and the Arthritis Foundation by including the following language: “The authors wish to acknowledge CARRA, and the ongoing Arthritis Foundation financial support of CARRA.” Refer to the current Publication and Presentation Guidlines for complete details.
IMPORTANT NOTE FOR TRANSDISCIPLINARY RESEARCH GRANT APPLICANTS USING CARRA REGISTRY DATA/SAMPLES
Grant applicants that intend to utilize the CARRA Registry or CARRA-related data and/or samples (including Legacy Registry and APPLE data/samples) must receive approval from the CARRA Data Sample Share Committee (DSSC) prior to submitting their grant applications. Applicants will be required to provide documentation of DSSC approval at the time of submitting a grant application. The request must match the intended use outlined in the grant proposal. Failure to receive approval of the data and/or sample request prior to submission of the grant application will result in the administrative decline of the application.
Data/sample requests take up to 4 weeks for review and approval. Please keep this in mind as you plan your grant application. For more information on requesting data/samples and to access the request form, please visit the CARRA Data and Samples Request area of the wiki.
If you have any questions regarding this requirement, email [email protected].
In addition, if your application will propose collection of any new data or biosamples via the CARRA Registry, you must include a letter of support (LOS) from CARRA's Research and Registry Oversight Committee (RROC). Email [email protected] with a brief summary of your proposal and CARRA will work to schedule a call with you to discuss your application as soon as possible.