Grants & Funding

CARRA-Arthritis Foundation Implementation Science Testing Grant


Not currently accepting applications

Project Period Length: 2 years

Max Funding Amount: $150,000 total ($75,000 per year)

Grant Availability: 2 awards

The Spring 2022 cycle is now closed:

  • DSSC/RROC requests: February 1, 2022
    • Only applies to applications intending to utilize CARRA Registry data/CARRA-related data and/or samples, and to applications proposing the collection of new data and/or biosamples. Click here for full details.
  • Letter of Intent due: February 14, 2022
  • Application portal opens: February 14, 2022
  • Application portal closes: March 14, 2022, 11:59 PM (CST)

Summary:  This funding opportunity is intended to support an Implementation Science Small Testing project.  The overall goal of the CARRA-Arthritis Foundation Implementation Science Funding Program is to support research projects that test strategies designed to improve the implementation of evidence-based practice into clinical settings for the care of patients with pediatric rheumatic conditions.  The current Implementation Science Small Testing Grant is intended to support the evaluation of one or more implementation strategies across several (at least 3) sites. Applicants must have already completed preliminary design work for the implementation strategy/strategies to be eligible to apply for this grant.  Researchers who seek to receive support to develop their implementation ideas further should instead apply to the Implementation Science Design Grant.

  • Click here for a glossary of implementation science terms
  • Click here for implementation science FAQs

 

Background and Focus: 

There is a gap between what is known from research to optimize the health of children and young people with rheumatological conditions and what is implemented in everyday practice.  Implementation science is intended to close this gap through discovering methods that effectively promote the systematic uptake of evidence-based practices into routine clinical care.   Implementation is an iterative process centered on adapting evidence for specific contexts and incorporating evidence in a sustainable way into decision-making and clinical workflows.

The current funding opportunity seeks to fund projects that incorporate active implementation strategies leading to uptake and integration of pediatric rheumatology research evidence into real-world practice settings across at least 3 sites, with the aim of increasing accessibility, usefulness, uptake, and/or impact of the research evidence among targeted end-users. Specific strategies proposed should be suitable for the finding(s) being implemented, the target population, and overall goals of the proposed project.  Applicants should include an explicit evaluation plan that details how they will determine successful execution of the implementation strategy and impact on health care/health outcomes.  Examples of common outcomes for implementation science projects include acceptability, adoption, appropriateness, feasibility, fidelity, implementation cost, and sustainability.

Applications should also describe plans for completing the following project activities:

  • Incorporating the perspectives and experiences of rheumatology patients, caregivers, and/or other stakeholders
  • Developing and piloting a data collection strategy to assess data collection timeliness and accuracy
  • Collecting and reviewing baseline data
  • Selecting the implementation strategy(ies) to improve performance
  • Producing implementation protocols, materials and tools (change package/bundle)
  • Employing process improvement methodologies (e.g., process mapping, failure mode and effects analysis, plan-do-study-act cycles) to plan and implement test changes and assess their impact
  • Assessing successes and failures and refine implementation protocols, materials, and tools

Additionally, proposed implementation strategies should incorporate the perspectives and experiences of rheumatology patients, caregivers, and/or other stakeholders.


CARRA-Arthritis Foundation Implementation Science Testing Grant Required Submission Materials

  • Letter of Intent (LOI)
    • A Letter of Intent (LOI) is required for this award. Please submit to [email protected] by midnight on February 14, 2022.
    • The LOI should be a one-page signed letter which includes:
      • A summary of the full proposal with a short description of aims of the project involved, with a clear indication of how the aims align with the intent of this application request
      • Name of the PIs and submitting institutions and an attestation that all PIs have knowledge of and support a forthcoming proposal
      • A list of key personnel and role(s)
      • A description of how the project aligns with CARRA's mission.
    • The LOI must be on institutional letterhead and signed by the Corresponding Principal Investigator.
    • While the LOI is an administrative requirement, it is for informational purposes only. Approval from CARRA is not needed to proceed with the full application. Investigators will receive confirmation that their LOI has been received by the CARRA grants office.
  • Project Summary/Abstract (300 work max)
  • Lay Summary (150 word max)
  • Testing Plan (5-page limit) (Download template: WORD)
  • Project Timeline (2 page limit) (Download template: WORD)
  • References (no page limit) (Download template: WORD)
  • Budget Table (2 page limit) (Download template: WORD)
    • All Primary Investigators (PIs) are required to dedicate effort on their projects, with the amount of effort indicated on the budget table. Requesting salary support is optional.
  • Budget Justification (Download template: WORD)
    • Important budget considerations:
      • The funding maximum limit is $150,000 over two years ($75,000 per year). If indirects are requested, they must be inclusive of the maximum funding amount of $150,000 and must not exceed the maximum allowable indirect amount of 8%. Please review CARRAs statement of direct and indirect support.
      • Salary support for PI(s) and Co-I(s) is allowable, but the total must not exceed 50% of total project costs. PI/Co-I salary support will be limited to a base-salary cap of $200,000 but can include payment of local fringe rates (on top of $200,000 salary cap).
      • Poster printing and publication costs are not allowed.
      • Travel expense requests are not permitted unless required for the conduct of research. Travel expenses to attend meetings to present this work, for example, are not allowed. 
  • Biosketches for all Principal Investigator(s), Co-Principal Investigator(s), and all Co-Investigator(s) using current NIH format (limit 5 pages per biosketch; please combine all biosketches into one PDF with the PI(s) biosketch listed first.)
  • Letters of support
    • A letter of support from the PI’s division chief documenting that the % effort will be protected from other work, and confirming investigator salary (if applicable), must be submitted with each application. If the PI is the division chief, a letter of support from the Department Chairperson is required.
    • Letters of support from collaborators, mentors and institution as applicable are highly recommended.
    • **Applications proposing the collection of any new data or biosamples via the CARRA Registry and/or via CARRA sites must obtain and include a letter of support (LOS) from CARRA's Research and Registry Oversight Committee (RROC). Applications that intend to use existing Registry data and/or samples must request approval from the Data and Sample Share Committee (DSSC). Read full details below.
  • Research Assurances
    • Funds will not be released until either: 1) an IRB approval letter is submitted; or 2) correspondence is submitted confirming that the IRB has determined your project is exempt research.
  • Appendix (limit 1 attachment)

Applicants must use the templates provided when submitting their final applications.

CARRA Staff is available to assist with the application process and to answer questions. Contact us by emailing [email protected]APPLICATIONS NOT FOLLOWING THESE INSTRUCTIONS WILL NOT BE CONSIDERED.


Eligibility

  • The project PI for all grants must be a current CARRA member who is up to date on membership dues and membership information (location, contact information, and membership status) is up-to-date.
  • Applicants who are awardees from previous grant cycles must have all active CARRA-Arthritis Foundation grant projects completed and have submitted a final progress report to be eligible to apply for this grant
  • MD applicants must be at a faculty level to be eligible to submit proposals.
  • Those eligible apply as PI include Voting Members, Emeritus Members, Research Professional Member - Investigators, and Associate Physician Members
  • Priority will be given to new and/or early investigators.
  • All grants must have a pediatric rheumatologist named as a PI or Co-Investigator.
  • Research Coordinator Member- Others, Health Care Professional Members, Fellow Members, and CARRA Executive Committee and Board of Directors members are not eligible to apply.

Funding Details

  • Year 1 and Year 2 funding will be provided upfront to the awardees institution in a single payment to be set up in a sundry account and used by the principal investigator according to the project budget.
  • Funds will not be released until either: 1) an IRB approval letter is submitted; or 2) correspondence is submitted confirming that the IRB has determined your project is exempt research.
  • For projects requesting budget support to cover Registry costs, requested funds will be held at CARRA and paid directly to DCRI.  Note that a letter of support from CARRA's Research and Registry Oversight Committee (RROC) is required for any project involving registry data or biosamples (see full details below).
  • If the project is not completed within the project period, the award recipient may request a no-cost extension (NCE) for up to 12 months. Requests for NCEs can be made up to 90 days prior, but no less than 30 days prior, to the project end date. An interim progress report must be submitted with the NCE Request Form, both of which are available on the CARRA website.
  • If the PI is unable to complete the project, any unexpended balance must be returned to CARRA.

Review Criteria Specific to Implementation Science Testing

  • Quality of preliminary design work: Quality of barriers assessment and key driver diagram, selection of measures, choice of Implementation Science Framework
  • Readiness of the intervention for implementation
  • Technical merit of the proposed implementation project
  • Feasibility
  • Project personnel and environment
  • Patient-centeredness and other stakeholder engagement
  • Importance to pediatric rheumatology, the Arthritis Foundation and CARRA

Reporting Requirements

  • Awardees must submit an interim progress report no later than 30 days after the end date of the first year of the award
  • Awardees must submit a final progress report no later than 60 days after the project period end date.
  • If the project cannot be completed within the original timeline, awardees may request one No-Cost Extension (NCE) to continue the project for up to 12 months. Requests for NCEs can be made up to 90 days prior, but no less than 30 days prior, to the project period end date. An interim progress report must be submitted with the NCE Request Form, both of which are available on the CARRA website

Presentations & Publications

  • All awardees of CARRA-Arthritis Foundation funding must abide by the procedures outlined in the CARRA Publications Policy when presenting/publishing findings from their projects. This includes submitting all abstracts and manuscripts to the CARRA Publications Committee for approval prior to submission and acknowledging the support of CARRA and the Arthritis Foundation by including the following language: The authors wish to acknowledge CARRA, and the ongoing Arthritis Foundation financial support of CARRA.” Refer to the current Publication and Presentation Guidelines for complete details.
  • Awardees are expected to submit abstracts to CARRA and present their findings at the CARRA Annual Scientific Meeting(s) until the project is complete/final.
  • Awardees are expected to submit a peer-reviewed abstract to another scientific meeting based on the funded project.

IMPORTANT UPDATE FOR GRANT APPLICANTS USING CARRA REGISTRY DATA/SAMPLES

Grant applicants that intend to utilize the CARRA Registry or CARRA-related data and/or samples (including Legacy Registry and APPLE data/samples) must receive approval from the CARRA Data Sample Share Committee (DSSC) prior to submitting their grant applications. These requests take 4-6 weeks to process.

For more information on requesting data/samples and to access the request form, please visit the CARRA Data and Samples Request area of the wiki. The deadline for 2022 Spring Grant Cycle DSSC requests is February 1, 2022.

Grant applications that propose collection of any new data or biosamples via the CARRA Registry and/or via CARRA sites must include a letter of support (LOS) from CARRA’s Research and Registry Oversight Committee (RROC). The deadline for 2022 Spring Grant Cycle RROC requests is February 1, 2022.

Applications that do not meet these request deadlines will result in an administrative decline. If you have any questions regarding this requirement, email [email protected].