Grants & Funding

CARRA-Arthritis Foundation Mentored Career Development Award

Not currently accepting applications

The CARRA-Arthritis Foundation Career Development Award is intended to support an early career investigator (3rd year fellow or Assistant Professor) who demonstrates a clear track record and commitment to developing an independent research career in the field of pediatric rheumatology.

Project Period Length: 3 years (Year 3 funding is contingent on adequate progress in years 1 and 2. See details below.)

Max Funding Amount: $375,000 total ($125,000 per year)

Grant Availability: 1 award


The Spring 2022 cycle is now closed:

  • DSSC/RROC requests due: February 1, 2022
    • Only applies to applications intending to utilize CARRA Registry data/CARRA-related data and/or samples, and to applications proposing the collection of new data and/or biosamples. See full details below.
  • Letters of Intent due: February 14, 2022
  • Application portal opens: February 14, 2022
  • Application portal closes: March 14, 2022, 11:59 PM (CST)

CARRA-Arthritis Foundation Career Development Grant Required Submission Materials

Read the following instructions carefully. Be sure to be compliant with margins and page limits. Use of the document templates provided is REQUIRED. Submit your completed grant application via the online grant submission system.

  • Letter of Intent (LOI)
    • An LOI is required when submitting a Career Development Award application and is due 30 days prior to the application deadline.
    • The LOI should be a one-page signed letter which includes:
      • A summary of the full proposal with a short description of aims of the project involved, with a clear indication of how the aims align with the intent of this RFA.
      • Name of the PI and submitting institution.
      • A list of key personnel and role(s).
      • A description of how the project aligns with CARRA's mission.
    • The LOI must be on institutional letterhead and signed by the Principal Investigator.
    • While the LOI is an administrative requirement, it is for informational purposes only. Approval from CARRA is not needed to proceed with the full application. Investigators will receive confirmation that their LOI has been received by the CARRA grants office.
  • Project summary/abstract (300 word max)
  • Lay summary (150 word max)
  • Project timeline (3 page limit) (Download template: WORD)
  • Specific aims (1 page limit) (Download template: WORD)
  • Research plan (6 page limit) (Download template: WORD)
  • References (no page limit) (Download template: WORD)
  • Career development plan (3 page limit) (Download template: WORD)
  • Mentor personal statement and letter of recommendation (Download template: WORD)
  • Budget table (3 page limit) (Download template: WORD)
    • All Principal Investigators (PIs) are required to dedicate effort on their projects which must be noted on the budget table.
    • A letter of support is required from your division chief guaranteeing
      • 1) 75% dedicated research effort, with at least 50% dedicated to this project, and
      • 2) investigator salary support. If the PI is the division chief, a letter from the Department Chairperson is required.
  • Budget justification (no page limit) (Download template: WORD)
    • Salary support: Total annual costs of salary support for the PI must not exceed $75,000, including up to 8% F&A.
    • Research support: Total annual costs for this project must not exceed $50,000, including up to 8% F&A. Funds cannot be used to purchase laboratory equipment which exceeds a cost of $5,000.
    • Poster printing and publication costs are allowed.
    • Travel expense requests are permitted if required for the conduct or presentation of research.
    • Other expenses should be discussed with CARRA personnel prior to application submission.
  • NIH-formatted Biosketches for all Principal Investigator(s), Co-Principal Investigator(s), and all Co-Investigator(s) (limit 5 pages per biosketch; please combine all biosketches into one PDF with the PI(s) biosketch listed first.)
  • Required letters of support
    • Letter from primary mentor detailing her/his role in the project and career development plan.
    • Letter from division chief documenting that 75% research effort is available, and confirming investigator salary.
    • Letters from secondary mentors and key collaborators are encouraged.
  • Research assurances
    • Submit documentation of an Institutional Review Board (IRB) review. Funds will not be released until either 1) IRB approval letter or 2) IRB waiver/documentation that IRB has determined your project is exempt from IRB review is received.
    • Awards will be relinquished if IRB approval or an IRB waiver is not received by 6 months after the project period start date.
  • Appendix (limit 1 attachment)

Important Information for Career Development Award Submissions

  • Funds will be provided to the awardee’s institution to be used by the principal investigator according to the project budget.
  • If the PI is unable to complete the project, any unexpended balance must be returned.
  • Awardees are expected to submit an abstract(s) and attend the CARRA Annual Scientific Meeting(s) until the project is complete/final results have been presented.
  • Please review CARRA’s statement of direct and indirect support.
  • Applicants will be notified of funding decisions by late May, 2022.
  • If the project is not completed within the project period, the award recipient may request a no-cost extension (NCE) for up to 12 months.  Requests for NCEs can be made up to 90 days prior, but no less than 30 days prior, to the project period end date. An interim progress report must be submitted with the NCE Request Form.  NCE requests will be considered by the review committee but are not guaranteed.
  • Awardees must submit a final progress report no later than 45 days after the project period end date.
  • All awardees must acknowledge the support from this funding mechanism in all presentations and publications related to this project by including the following language: “The authors wish to acknowledge CARRA, and the ongoing Arthritis Foundation financial support of CARRA for this work.”
  • Recipients must abide by CARRA’s relevant organizational policies and guidelines regarding publications.


  • MD applicants must be a 3rd year fellow or Assistant Professor to be eligible to submit proposals.
  • Fellow applicants must provide a letter of commitment from their current or future institution contingent on funding.
  • All grants must be submitted by or have a pediatric rheumatologist named as a Co-Investigator.
  • Applicants must be CARRA members in good standing.

Review Process

Applications will be submitted via an online submission form. The CARRA Grants Manager will conduct an administrative review to ensure all necessary application materials have been submitted. Reviews will be conducted by the Scientific Review Committee (SRC). SRC recommendations and scores will then  be reviewed by the Internally Funded Research Oversight Committee (IROC) for final funding decisions. Applicants will be notified via email and must return a signed award acknowledgement and other appropriate documentation as needed before funds are distributed.

Additional Details

3 Year Funding

Funds will be provided to the awardee’s institution in two payments to be set up in a sundry account and used by the principal investigator according to the project budget.

  • Year 1 funding as outlined in the budget justification will be provided upfront.
  • Year 2 funding as outlined in the budget justification will distributed following submission and approval of an interim progress report at the end of year 1. Release of Year 2 funds may be contingent on IRB annual re-approval.
  • Year 3 funding will be awarded if adequate progress is made in Years 1 and 2.

Reporting Requirements

  • Awardees must submit a year 1 progress report 30 days prior to the end of the first year of the project period in order to request the release of year 2 funds.
  • Awardees must submit a year 2 progress report 30 days prior to the end of the second year of the project period in order to request the release of year 3 funds.


Grant applicants that intend to utilize the CARRA Registry or CARRA-related data and/or samples (including Legacy Registry and APPLE data/samples) must receive approval from the CARRA Data Sample Share Committee (DSSC) prior to submitting their grant applications. These requests take 4-6 weeks to process.

For more information on requesting data/samples and to access the request form, please visit the CARRA Data and Samples Request area of the wiki.

The deadline for 2022 Spring Grant Cycle DSSC requests is February 1.


Grant applications that propose collection of any new data or biosamples via the CARRA Registry must include a letter of support (LOS) from CARRA’s Research and Registry Oversight Committee (RROC).

The deadline for 2022 Spring Grant Cycle RROC requests is February 1.


Applications that do not meet these request deadlines will result in an administrative decline. If you have any questions regarding this requirement, email [email protected]